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Aerenchyma formation in rice roots follows a well designated cell fate....

Aerenchyma formation in rice roots follows a well designated cell fate. Lysigenous gas-space formation initiates at specific position of the mid cortex and expand toward basal portion of rice seminal...

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PCD occurs in plant life cycle. PCD is involved in many phases through...

PCD occurs in plant life cycle. PCD is involved in many phases through vegetative and reproductive development and response to environmental stresses [See Color Plate 6, Fig. 12]

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Mutagenicity testing of nivalenol

Mutagenicity testing of nivalenol

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Effect of BAPTA-AM on nivalenol-induced secretion of IL-8 in HL60 cells

Effect of BAPTA-AM on nivalenol-induced secretion of IL-8 in HL60 cells

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Agarose gel electrophoresis of DNA from nivalenol-treated HL60 cells. Lane...

Agarose gel electrophoresis of DNA from nivalenol-treated HL60 cells. Lane 1: molecular weight marker (100-bp DNA ladder). Lane 2: negative control (treated with vehicle only). Lanes 3–6: treated with...

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Flow cytometry histogram overlay of FAM-VAD-FMK-treated tumor cells taken...

Flow cytometry histogram overlay of FAM-VAD-FMK-treated tumor cells taken from either the saline-treated or the ATO-treated tumor masses (unpublished data). In these results, the tumors were scraped...

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In vivo apoptosis detection in an ATO-treated mouse, 7-day-old SCK tumor....

In vivo apoptosis detection in an ATO-treated mouse, 7-day-old SCK tumor. The test mouse received an ATO (8 mg/kg IP injection). The test mouse subsequently received an IV injection of 8.0 μg cell...

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Extracellular functions mediated by galectin-3. The secreted galectin-3...

Extracellular functions mediated by galectin-3. The secreted galectin-3 potentiates angiogenesis by facilitating migration, chemotaxis and morphogenesis of endothelial cells. It also induces T cell...

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Reversine promoted apoptosis through the activation of caspases in SW579...

Reversine promoted apoptosis through the activation of caspases in SW579 cells. (a) Cells were incubated with reversine for various dosages and the caspase-3, -8 and -9 were detected by western blot....

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Reversine promoted apoptosis through the activation of caspases in SW579...

Reversine promoted apoptosis through the activation of caspases in SW579 cells. (a) Cells were incubated with reversine for various dosages and the caspase-3, -8 and -9 were detected by western blot....

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Detection of reversine mediated apoptosis in human thyroid cancer cells....

Detection of reversine mediated apoptosis in human thyroid cancer cells. Cells were incubated with DMSO or with reversine in various dosages, and the apoptotic cells of (A and B) ARO, (C and D) WRO...

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Detection of reversine mediated apoptosis in human thyroid cancer cells....

Detection of reversine mediated apoptosis in human thyroid cancer cells. Cells were incubated with DMSO or with reversine in various dosages, and the apoptotic cells of (A and B) ARO, (C and D) WRO...

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Detection of reversine mediated apoptosis in human thyroid cancer cells....

Detection of reversine mediated apoptosis in human thyroid cancer cells. Cells were incubated with DMSO or with reversine in various dosages, and the apoptotic cells of (A and B) ARO, (C and D) WRO...

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Reversine induced cell cycle progression arrest at the G2/M phase and cell...

Reversine induced cell cycle progression arrest at the G2/M phase and cell death in human thyroid cancer cells. Cells were incubated with reversine with various dosages and the DNA content of (a) ARO,...

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Reversine induced cell cycle progression arrest at the G2/M phase and cell...

Reversine induced cell cycle progression arrest at the G2/M phase and cell death in human thyroid cancer cells. Cells were incubated with reversine with various dosages and the DNA content of (a) ARO,...

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Reversine inhibited the growth of human thyroid cancer cells. Cells were...

Reversine inhibited the growth of human thyroid cancer cells. Cells were incubated with reversine for 24, 48 and 72 h, and the effects on the proliferation inhibition of (a, b) ARO, (c, d) WRO and (E...

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Reversine inhibited the growth of human thyroid cancer cells. Cells were...

Reversine inhibited the growth of human thyroid cancer cells. Cells were incubated with reversine for 24, 48 and 72 h, and the effects on the proliferation inhibition of (a, b) ARO, (c, d) WRO and (E...

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Reversine inhibited the growth of human thyroid cancer cells. Cells were...

Reversine inhibited the growth of human thyroid cancer cells. Cells were incubated with reversine for 24, 48 and 72 h, and the effects on the proliferation inhibition of (a, b) ARO, (c, d) WRO and (E...

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The C-terminal region of AtBI-1 is essential for the cell death inhibition....

The C-terminal region of AtBI-1 is essential for the cell death inhibition. The C-terminal 14 amino acids of AtBI (original) were replaced in mutants (AtBI-28-32). The score for the coiled-coil...

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Biological processes leading to oxidative stress-induced cell death. Abiotic...

Biological processes leading to oxidative stress-induced cell death. Abiotic and biotic stresses lead to ROS accumulation, which triggers orchestrated events in plant cells

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Morphological changes in mitochondria during ROS-induced plant cell death....

Morphological changes in mitochondria during ROS-induced plant cell death. Mitochondria were observed by electron microscope at 0 (control, left) or 3 days (right) after cell death induction...

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AFMC neither induce expression of DR5 nor enhance TRAIL-induced apoptosis in...

AFMC neither induce expression of DR5 nor enhance TRAIL-induced apoptosis in WI-38 cells. Figure 6A: WI-38 cells were treated with AFMC for 30 min and then treated with TRAIL for 24 h at the indicated...

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Effects of AFMC and/or TRAIL on apoptosis and DRs expression of H460 and H157...

Effects of AFMC and/or TRAIL on apoptosis and DRs expression of H460 and H157 cells. Figure 5A: Cells were treated with 1.0 μmol/L AFMC or 30 ng/mL TRAIL for 24 h or the pretreated with 1.0 μmol/L AFMC...

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Effects of DR5/Fc and DR5 siRNA on AFMC-induced DR5 expression and...

Effects of DR5/Fc and DR5 siRNA on AFMC-induced DR5 expression and AFMC/TRAIL-induced apoptosis. Figure 4A: A549 cells were transfected with LacZ siRNA or siRNA against DR5 followed by treatment with...

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AFMC increases DR5 protein levels in A549 cells. Figure 3A: A549 cells were...

AFMC increases DR5 protein levels in A549 cells. Figure 3A: A549 cells were treated with the indicated concentrations of AFMC for 24 h, and DR5 levels were measured by Western blotting. β-actin was...

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Effects of AFMC and/or TRAIL on the caspase activities of A549 cells. Figure...

Effects of AFMC and/or TRAIL on the caspase activities of A549 cells. Figure 2A: Enzymatic activities of caspase -3, -8 and -9 were determined by incubation of 20 μg of total protein with 200 μmol/L...

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Cytotoxic and apoptotic activities of AFMC or TRAIL or both on A549 cells....

Cytotoxic and apoptotic activities of AFMC or TRAIL or both on A549 cells. Figure 1A: A549 cells were treated with AFMC for 30 min and then treated with or without TRAIL for 24 h at the indicated...

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Albendazole acts synergistically with radiation in MM and SCLC cells.

Albendazole acts synergistically with radiation in MM and SCLC cells.

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ABZ induces a lower SF2 (ie supra-additive) than the expected added SF2...

ABZ induces a lower SF2 (ie supra-additive) than the expected added SF2 (EAS) calculated by adding the effect of radiation alone and ABZ alone.

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Albendazole arrests cell in the G2/M phase in a time and dose dependent fashion.

Albendazole arrests cell in the G2/M phase in a time and dose dependent fashion.

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ABZ treatment potentiates apoptosis in irradiated melanoma and SCLC cells....

ABZ treatment potentiates apoptosis in irradiated melanoma and SCLC cells. A2058 and H1530 cells were treated with 500 nM ABZ, 2 Gy or 10 Gy radiation, or indicted combination. Proteins were analyzed...

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Treatment with albendazole sensitizes MM and SCLC cells to ionizing...

Treatment with albendazole sensitizes MM and SCLC cells to ionizing radiation. Radiosensitization by albendazole was assessed on the basis of clonogenic cell survival assays. H446 (A), H1530 [2], A375...

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Albendazole inhibits proliferation of MM and SCLC cells. A375 (○), A2058 (□),...

Albendazole inhibits proliferation of MM and SCLC cells. A375 (○), A2058 (□), H1530 (◊) and H446 cells (Δ) were treated with increasing concentrations of ABZ for 12 hours (A) or 72 hours [2]. Points,...

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Albendazole treatment causes phosphorylation of H2AX. A2058 melanoma cells...

Albendazole treatment causes phosphorylation of H2AX. A2058 melanoma cells received no treatment (-) or treatment with 500 nM albendazole (ABZ) or 1 μM cisplatin (CIS) for 9 hr. Extracted proteins...

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Main functions of the ER. Through SEC61 channels proteins are...

Main functions of the ER. Through SEC61 channels proteins are cotranslationally imported into the ER lumen where they become glycosylated (only relevant sugar residues shown for clarity; G glucose, M...

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Proposed model of calcium flux and BI-1. BI-1 may regulate calcium flux at...

Proposed model of calcium flux and BI-1. BI-1 may regulate calcium flux at ER in response to stresses, leading to inhibition of cell death in plant cells. ROS stimulation caused by various stress...

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Effects of SS-31 treatment on survival rate. SS-31 treatment did not result...

Effects of SS-31 treatment on survival rate. SS-31 treatment did not result in increased survival rate after CLP. The survival rates were estimated by the Kaplan-Meier method and compared by log-rank...

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Effects of SS-31 on TUNEL-positive cells. TUNEL-positive cells in the lung,...

Effects of SS-31 on TUNEL-positive cells. TUNEL-positive cells in the lung, kidney, and liver were significantly increased after CLP when compared with the control + vehicle group, while SS-31...

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Effects of SS-31 on organ NF-κBp65 and iNOS expressions. Lung, kidney, and...

Effects of SS-31 on organ NF-κBp65 and iNOS expressions. Lung, kidney, and liver levels of NF-κB p65 and iNOS were significantly increased after CLP, whereas SS-31 treatment significantly inhibited...

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Effects of SS-31 on organ histological scores. CLP-induced increased lung,...

Effects of SS-31 on organ histological scores. CLP-induced increased lung, kidney, and liver histological scores, whereas SS-31 treatment significantly attenuated these increased histological scores...

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Effects of SS-31 on organ ROS generation, ATP levels, MPO activity, and W/D...

Effects of SS-31 on organ ROS generation, ATP levels, MPO activity, and W/D ratio. CLP-induced increased ROS and decreased ATP levels were reversed by treatment of SS-31. Pulmonary MPO activity and...

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Effect of SS-31 on inflammatory cytokines. The serum level of TNF-α, IL-1β,...

Effect of SS-31 on inflammatory cytokines. The serum level of TNF-α, IL-1β, and IL-6 were significantly increased at 6 h after CLP. SS-31 treatment markedly suppressed only the increase of TNF-α at 6...

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Effects of SS-31 on oxidative product and antioxidant enzymatic activities....

Effects of SS-31 on oxidative product and antioxidant enzymatic activities. CLP resulted in significantly increased MDA in serum and tissues when compared with those of the control + vehicle group....

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Effects of SS-31 on organ dysfunction-associated indicators. CLP...

Effects of SS-31 on organ dysfunction-associated indicators. CLP significantly increased decreased PO2 and increased serum levels of ALT, BUN, and Cr than those of the control + vehicle group. SS-31...

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Cluster analysis to compare the fold changes in gene expression in cells...

Cluster analysis to compare the fold changes in gene expression in cells treated by A23187

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The effect of COG on Bax/Bcl balance. A: control; B: AA; C:AA + Dex (2...

The effect of COG on Bax/Bcl balance. A: control; B: AA; C:AA + Dex (2 mg/kg); D: AA + COG (20 mg/kg); E: AA + COG (40 mg/kg) Values are expressed as means ± SDs. Compared with control:# P 

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The effect of COG on apoptosis in AA rats (×200).

The effect of COG on apoptosis in AA rats (×200).

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Histological assessments (×200). Values are expressed as means ± SDs....

Histological assessments (×200). Values are expressed as means ± SDs. Compared with control: # P 

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The effect of COG on cytokine in serum. Values are expressed as means ± SDs....

The effect of COG on cytokine in serum. Values are expressed as means ± SDs. Compared with control: # P 

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The effect of COG on rat HPV. Values are expressed as means ± SDs. Compared...

The effect of COG on rat HPV. Values are expressed as means ± SDs. Compared with control: # P 

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